Protein Purification
MilliporeSigma™ Calbiochem™ PARP Inhibitor IX, EB-47
The PARP Inhibitor IX, EB-47 controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ RNA Polymerase I Inhibitor II, BMH-21
A cell-permeable compound that blocks the growth and viability of a variety of cancer cell lines (GI50 = 160 nM in NCI-60 cells), but does not affect normal cells.
MilliporeSigma™ Calbiochem™ Calpastatin, Human, Recombinant, Domain I
Domain I of human calpastatin.
MilliporeSigma™ Calbiochem™ InSolution™ PKR Inhibitor
The InSolution™ PKR Inhibitor, also referenced under CAS 608512-97-6, controls the biological activity of PKR. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Bax Channel Blocker
A cell-permeable dibromocarbazolo-piperazinyl derivative that displays anti-apoptotic properties.
MilliporeSigma™ Calbiochem™ α-Secretase Substrate II, Fluorogenic
An internally quenched fluorogenic peptide substrate containing the α-secretase cleavage site of β-Amyloid Precursor Protein (APP).
MilliporeSigma™ Calbiochem™ PARP Inhibitor XIV
The PARP Inhibitor XIV, also referenced under CAS 1104546-89-5, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ D-Amino Acid Oxidase Inhibitor III, AS057278
A cell-permeable pyrazolocarboxylic acid that acts as a selective D-amino acid oxidase (DAO/DAAO/DAMOX/OXDA) inhibitor (IC50 = 910nM against human DAO; [D-ser] = 10 mM) and effectively protects DAO overexpressing cultures from oxidative stress-induced cell death upon D-Ser (50 mM) exposure (ED50
MilliporeSigma™ Calbiochem™ Phenylarsine Oxide
A membrane-permeable protein tyrosine phosphatase inhibitor (IC50 = 18 μM).
MilliporeSigma™ Calbiochem™ HNMPA-(AM)3
A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases.
MilliporeSigma™ Calbiochem™ PPACK, Dihydrochloride
PPACK, Dihydrochloride, CAS 142036-63-3, is an extremely potent and selective irreversible inhibitor of thrombin (Kobs/[I] = 107M-1S-1). Reacts with thrombin in a 1:1 stoichiometry.
MilliporeSigma™ Calbiochem™ Wnt Agonist II, SKL2001
The Wnt Agonist II, SKL2001 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Biochemicals applications.
MilliporeSigma™ Calbiochem™ Ru360
A cell-permeable oxygen-bridged dinuclear ruthenium amine complex that has been shown to bind to mitochondria with high affinity (Kd = 340 pM).
MilliporeSigma™ Calbiochem™ ISR Inhibitor, ISRIB
The cell-permeable, selective inhibitor of eIF2α/eIF2S1 Ser51 phosphorylation-initiated UPR response (≈25 to 200 nM) upon ER stress induction.
MilliporeSigma™ Calbiochem™ Autotaxin Inhibitor II, HA130
A thiazolidinedione that is designed to target the ATX active site thr210 with a boronic moiety and shown to potently inhibit ATX lysoPLD activity (IC50 ∽28nM using recombinant human ATX or human plasma) in a reversible manner with a mixed-type Lineweaver-Burk kinet